Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1-(3-Azidopropyl)-4-fluorobenzene → 3-(4-Fluorophenyl)propan-1-amine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1-(3-Azidopropyl)-4-fluorobenzene | HCID 58997701 | — |
| 촉매 | Palladium | HCID 23938 | — |
| 용매 | Methanol | HCID 887 | — |
| 생성물 | 3-(4-Fluorophenyl)propan-1-amine | HCID 6483796 | 57.1% |
반응 단계
The product from step e (0.79 g, 6.4 mmol) was dissolved in 100 mL of MeOH and added carefully to 0.20 g of 10% Pd/C under N2. The mixture was hydrogenated in a Parr shaker at 50 PSI overnight. Filtration through fiberglass filter paper under N2 and under vacuum yielded 0.56 g of a clear colorless oil.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07291744B2 |
| 출처 데이터셋 | uspto-grants-2007_11 |
| ORD ID | ord-e98aa9fc6dbc41d6b7b745af3d109ccc |
| 출처 메모 | uspto-grants-2007_11 |