참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Hydroxyamine hydrochloride | HCID 443297 | — |
| 반응물 | Sodium Acetate | HCID 517045 | — |
| 반응물 | Methyl 5-formyl-2-methoxybenzoate | HCID 10856352 | — |
| 용매 | Water ethanol | HCID 19096565 | — |
| 생성물 | Methyl 2-methoxy-5-formylbenzoate oxime | HCID 86583897 | — |
반응 단계
Combine methyl 2-methoxy-5-formylbenzoate (5.0 g, 25.9 mmol), hydroxylamine hydrochloride (8.55 g, 133 mmol), and sodium acetate (10.25 g, 125 mmol) in ethanol/water (200 mL, 1/1). Heat to 50° C. After 1 hour, pour the reaction mixture onto ice to give a solid. Collect the solid by filtration to give methyl 2-methoxy-5-formylbenzoate oxime: Rf =0.76 (silica gel, 9/1 dichloromethane/methanol).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US05977139 |
|---|
| 출처 데이터셋 | uspto-grants-1999_11 |
|---|
| ORD ID | ord-b3842bb5e69f48e5ac375187866c6f23 |
|---|
| 출처 메모 | uspto-grants-1999_11 |
|---|
