Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Triethylamine → 1-Methoxy-3-(1,2,3,4-tetrahydro-1-naphthyl)-thiourea
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Triethylamine | HCID 8471 | — |
| 반응물 | O-Methylhydroxylamine hydrochloride | HCID 521874 | — |
| 반응물 | 1-Isothiocyanato-1,2,3,4-tetrahydronaphthalene | HCID 21393478 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | 1-Methoxy-3-(1,2,3,4-tetrahydro-1-naphthyl)-thiourea | HCID 21393496 | — |
반응 단계
To an ice-cold, stirred mixture of 0.02 mole of methoxyamine hydrochloride and methylene chloride is added 0.02 mole of triethylamine. The mixture is then allowed to warm to about 15° C. to 25° C. while a solution of 0.01 mole of 1,2,3,4-tetrahydro-1-naphthyl isothiocyanate in methylene chloride is added dropwise. The mixture is stirred overnight at room temperature and then filtered. The filtrate is washed with water, dried (sodium sulfate), and the solvent evaporated at reduced pressure to give the title compound.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US03953506 |
| 출처 데이터셋 | uspto-grants-1976_04 |
| ORD ID | ord-6a07729a154d4098a9a71e74fc3b55bb |
| 출처 메모 | uspto-grants-1976_04 |