Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-Fluoro-4-(methoxycarbonyl)benzeneboronic acid → 2-Fluoro-4'-[3-(2-methyl-pyridin-4-yl)-3-oxo-1-o-tolyl-propyl]-biphenyl-4-carboxylic acid methyl ester
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-Fluoro-4-(methoxycarbonyl)benzeneboronic acid | HCID 24824345 | — |
| 반응물 | 3-(4-Bromo-phenyl)-1-(2-methyl-pyridin-4-yl)-3-o-tolyl-propan-1-one | HCID 66668180 | — |
| 생성물 | 2-Fluoro-4'-[3-(2-methyl-pyridin-4-yl)-3-oxo-1-o-tolyl-propyl]-biphenyl-4-carboxylic acid methyl ester | HCID 66666683 | — |
반응 단계
In analogy to example 74, step 6, from 3-(4-bromo-phenyl)-1-(2-methyl-pyridin-4-yl)-3-o-tolyl-propan-1-one (example 74, step 5) and 2-fluoro-4-(methoxycarbonyl)phenylboronic acid was prepared the title compound as a light brown oil, MS (ESI+): m/z=468.1961 ([M+H]+).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08765730B2 |
| 출처 데이터셋 | uspto-grants-2014_07 |
| ORD ID | ord-505d367c4e9a47a4bbe0e38af98db6ba |
| 출처 메모 | uspto-grants-2014_07 |