Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
D-Leucine, methyl ester → (R)-methyl 4-methyl-2-(5-methylbenzofuran-2-carboxamido)pentanoate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | D-Leucine, methyl ester | HCID 89967 | — |
| 반응물 | 5-Methyl-1-benzofuran-2-carboxylic acid | HCID 932007 | — |
| 생성물 | (R)-methyl 4-methyl-2-(5-methylbenzofuran-2-carboxamido)pentanoate | HCID 57527959 | — |
반응 단계
Prepared in a similar manner to example 4 using 5-methylbenzofuran-2-carboxylic acid (example 26a) and D-leucine methyl ester. 1H NMR (500 MHz, CDCl3): 0.98 (d, 3H, J=6.26 Hz), 1.00 (d, 3H, J=6.17 Hz), 1.56 (s, 3H), 1.76 (m, 3H), 2.48 (s, 3H), 3.78 (s, 3H), 4.86 (m, 1H), 6.95 (m, 1H), 7.23 (dd, 1H, J=8.54 Hz, J=1.55 Hz), 7.40 (m, 2H). 7.44 (dd, 1H, J=1.72, J=0.9 Hz). MS 304 (M+H, 304)
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08124121B2 |
| 출처 데이터셋 | uspto-grants-2012_02 |
| ORD ID | ord-50210147d2384836af62919c317638f4 |
| 출처 메모 | uspto-grants-2012_02 |