Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
N-(1-(2-(3,4-dimethoxyphenyl)ethyl)pyrrolidin-3-yl)phthalimide → 3-Amino-1-(2-(3,4-dimethoxyphenyl)ethyl)pyrrolidine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | N-(1-(2-(3,4-dimethoxyphenyl)ethyl)pyrrolidin-3-yl)phthalimide | HCID 15045352 | — |
| 용매 | Ethanol | HCID 702 | — |
| 용매 | Hydrazine hydrate (1:1) | HCID 24654 | — |
| 생성물 | 3-Amino-1-(2-(3,4-dimethoxyphenyl)ethyl)pyrrolidine | HCID 15045353 | 100.3% |
반응 단계
1.03 g of N-(1-(2-(3,4-dimethoxyphenyl)ethyl)pyrrolidin-3-yl)phthalimide was dissolved in 50 ml of ethanol, to which 2 ml of hydrazine monohydrate was added and refluxed under heating for 14 hours. The solvent was distilled off and an aqueous diluted solution of sodium hydroxide was added to the residue and extracted with chloroform. After drying with anhydrous magnesium sulfate, the solvent was distilled off, to obtain 0.68 g of the above-captioned compound (yield: 100%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05177089 |
| 출처 데이터셋 | uspto-grants-1993_01 |
| ORD ID | ord-7133ce3a17224f1e9223063767953259 |
| 출처 메모 | uspto-grants-1993_01 |