Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Phosphorus tribromide → 1-(Bromomethyl)-4-(dodecyloxy)benzene
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Phosphorus tribromide | HCID 24614 | — |
| 반응물 | 4-(Dodecyloxy)benzoic acid | HCID 75330 | — |
| 반응물 | 4-Dodecyloxybenzyl alcohol | HCID 14477628 | — |
| 반응물 | Aluminium lithium hydride | HCID 21226445 | — |
| 생성물 | 1-(Bromomethyl)-4-(dodecyloxy)benzene | HCID 23052179 | — |
반응 단계
According to customary procedures, 4-dodecyloxybenzoic acid was reduced with LiAlH4 and the formed 4-dodecyloxybenzyl alcohol was brominated with phosphorus tribromide to obtain 4-dodecyloxybenzyl bromide. Then, 2.0 g of the so-obtained compound was reacted with 1.0 g of p-acetoxyphenol in the presence of NaH in dimethylformamide to obtain 1.2 g of 4-dodecyloxybenzyl(4-acetoxyphenyl) ether. The so-obtained compounds was dissolved in a liquid mixture of tetrahydrofuran and an equimolar amount of 1N LiOH was added to the solution to remove the acetyl group, and post treatments were carried out according to customary procedures to obtain 1.0 g of 4-dodecyloxybenzyl(4-hydroxyphenyl) ether.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04925591 |
| 출처 데이터셋 | uspto-grants-1990_05 |
| ORD ID | ord-1fd78818d481421fa0a10518d412dee5 |
| 출처 메모 | uspto-grants-1990_05 |