참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | 1-(1-Naphthyl)piperazine | HCID 1342 | — |
| 반응물 | 1H-Isoindole-1,3(2H)-dione, 2-(2-bromoethyl)- | HCID 11325 | — |
| 반응물 | Potassium Carbonate | HCID 11430 | — |
| 용매 | Dimethylformamide | HCID 6228 | — |
| 생성물 | 2-{2-[4-(1-Naphthyl)-1-piperazinyl]ethyl}-1H-isoindole-1,3(2H)-dione | HCID 21096932 | — |
반응 단계
A suspension of 1.17 g (5.52 mmol) of 1-(1-naphthyl)piperazine (Tetrahedron Letters, 1998, 39(15), 2219-2222), 0.99 g (7.15 mol) of potassium carbonate and 1.68 g (6.62 mmol) of 2-(2-bromoethyl)-1H-isoindole-1,3(2H)-dione in 15 ml of N,N-dimethylformamide is heated at 90° C. for 2 hours.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US08034818B2 |
|---|
| 출처 데이터셋 | uspto-grants-2011_10 |
|---|
| ORD ID | ord-428adebbb3e043b3a4c3765d4dbe562d |
|---|
| 출처 메모 | uspto-grants-2011_10 |
|---|
