Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
3-Methyl-2-butenoyl chloride → HCID 57505645, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 3-Methyl-2-butenoyl chloride | HCID 102394 | — |
| 반응물 | N-{5-[(2-aminoimidazo[1,2-b]pyridazin-6-yl)oxy]-2-methylphenyl)-1,3-dimethyl-1H-pyrazole-5-carboxamide hydrochloride | HCID 57505635 | — |
| 용매 | Dimethylacetamide | HCID 31374 | — |
| 생성물 | HCID 57505645 | HCID 57505645 | 68% |
반응 단계
In the same manner as in Example 264 and using N-{5-[(2-aminoimidazo[1,2-b]pyridazin-6-yl)oxy]-2-methylphenyl}-1,3-dimethyl-1H-pyrazole-5-carboxamide hydrochloride (200 mg, 0.48 mmol), 3-methylbut-2-enoylchloride (81 μL, 0.73 mmol) and N,N-dimethylacetamide (5 mL) as starting materials, the title compound (150 mg, 68%) was obtained as a pale-yellow solid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08034812B2 |
| 출처 데이터셋 | uspto-grants-2011_10 |
| ORD ID | ord-b2305265517a487ca55788f506e02633 |
| 출처 메모 | uspto-grants-2011_10 |