Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1-(Trimethylsilyl)prop-1-yne → 1-(1,4-dioxa-spiro[4.5]dec-8-yl)-4-trimethylsilanyl-1H-[1,2,3]triazole
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1-(Trimethylsilyl)prop-1-yne | HCID 80363 | — |
| 반응물 | 8-Azido-1,4-dioxaspiro[4.5]decane | HCID 57424094 | — |
| 생성물 | 1-(1,4-dioxa-spiro[4.5]dec-8-yl)-4-trimethylsilanyl-1H-[1,2,3]triazole | HCID 57795425 | 105% |
반응 단계
A mixture of 8-Azido-1,4-dioxa-spiro[4.5]decane (1.00 g, 5.43 mmol) and 1-(trimethylsilyl)propyne (3.76 mL, 27.1 mmol) was submitted to microwave at 120° C. for 2 h. The mixture was concentrated under vacuum to remove the excess of 1-(trimethylsilyl)propyne and crude 1-(1,4-dioxa-spiro[4.5]dec-8-yl)-4-trimethylsilanyl-1H-[1,2,3]triazole (1.6 g, 105%) was obtained.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08158675B2 |
| 출처 데이터셋 | uspto-grants-2012_04 |
| ORD ID | ord-3f4a0932261f4295845f2833878ea275 |
| 출처 메모 | uspto-grants-2012_04 |