Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Bromine → 5-Bromo-2-methyl-4-(4-nitrophenyl)-1,3-thiazole
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Bromine | HCID 24408 | — |
| 반응물 | 2-Methyl-4-(4-nitrophenyl)thiazole | HCID 193689 | — |
| 용매 | Chloroform | HCID 6212 | — |
| 생성물 | 5-Bromo-2-methyl-4-(4-nitrophenyl)-1,3-thiazole | HCID 68998100 | 60% |
반응 단계
Bromine (6 mmol) was added dropwise to a solution of 2-methyl-4-(4-nitrophenyl)-1,3-thiazole (5 mmol) in chloroform (20 mL) and the solution refluxed for 4 h. The solvent was evaporated and the product purified by crystallization from ether to afford the title compound (60%). ESMS [M+H]+: 300.2
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07495102B2 |
| 출처 데이터셋 | uspto-grants-2009_02 |
| ORD ID | ord-d0c34458662e4028bdddffb6d44372ca |
| 출처 메모 | uspto-grants-2009_02 |