Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Triphosgene → 1-Hydroxy-4-adamantyl chloroformate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Triphosgene | HCID 94429 | — |
| 반응물 | Adamantane-1,4-diol | HCID 4252005 | — |
| 용매 | Pyridine | HCID 1049 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | 1-Hydroxy-4-adamantyl chloroformate | HCID 58171499 | — |
반응 단계
A solution of 1,4-adamantanediol (210 mg, 1.25 mmol) in dry pyridine (3 mL) and dry CH2Cl2 (6 mL) was cooled in an ice bath and a solution of triphosgene (122 mg, 0.41 mmol) in dry Ch2Cl2 (3 mL) was added dropwise over 5 min. The mixture was stirred in the ice bath for 3 h to afford a 0.1 M solution of 1-hydroxy-4-adamantyl chloroformate.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US09163012B2 |
| 출처 데이터셋 | uspto-grants-2015_10 |
| ORD ID | ord-08dce3b9c49c4bf7b2f13c4f1e925941 |
| 출처 메모 | uspto-grants-2015_10 |