참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Potassium Hydroxide | HCID 14797 | — |
| 반응물 | 2,3-Dichloronitrobenzene | HCID 18555 | — |
| 반응물 | 3-Chloropropanethiol | HCID 87134 | — |
| 용매 | Tetrahydrofuran | HCID 8028 | — |
| 생성물 | (2-Chloro-6-nitrophenyl)(3-chloropropyl)sulfane | HCID 22735865 | 100% |
반응 단계
To a dry THF (Aldrich anhydrous grade, 70 mL) solution of 2,3-dichloronitrobenzene (9.61 g, 50.1 mmol) and 3-chloropropanethiol (5.0 g, 45.5 mmol) was added in one portion at 23° C. KOH pellets. The resulting mixture was vigorously stirred at 23° C. for 3.5 h. The reaction mixture was filtered through a Celite plug to remove remaining KOH. The plug was washed with THF (2×50 mL). The filtrate was concentrated in vacuo to give crude 1-chloro-2-[(3-chloropropyl)sulfanyl]-3-nitrobenzene (12 g, ˜100%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | USRE039679E1 |
|---|
| 출처 데이터셋 | uspto-grants-2007_06 |
|---|
| ORD ID | ord-a9c15ca7bb9e4f46bb5ac21caee1abe9 |
|---|
| 출처 메모 | uspto-grants-2007_06 |
|---|
