Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Methyl Benzoate → 1-Benzoyl-N-tert-butylcyclopropane-1-sulfonamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Methyl Benzoate | HCID 7150 | — |
| 반응물 | N-tert-butyl-1-methylcyclopropane-1-sulfonamide | HCID 21889792 | — |
| 생성물 | 1-Benzoyl-N-tert-butylcyclopropane-1-sulfonamide | HCID 21889830 | 66% |
반응 단계
This compound was obtained in 66% yield using the procedure described for the synthesis of N-tert-Butyl-(1-methyl)cyclopropylsulfonamide except 1.2 equivalents of methyl benzoate was used as the electrophile. The compound was purified by column chromatography over SiO2 using 30% to 100% CH2Cl2 in hexane: 1H NMR (CDCl3) δ 1.31 (s, 9H), 1.52 (m, 2H), 1.81 (m, 2H), 4.16 (bs, 1H), 7.46 (m, 2H), 7.57 (m, 1H), 8.05 (d, J=8.5 Hz, 2H).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07741281B2 |
| 출처 데이터셋 | uspto-grants-2010_06 |
| ORD ID | ord-a44c3cd92f3e4d0d94826e01a47828e8 |
| 출처 메모 | uspto-grants-2010_06 |