Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
N'-[(3,4-dimethoxy-5-nitrobenzoyl)oxy]acetamidine → 5-(3,4-Dimethoxy-5-nitrophenyl)-3-methyl-1,2,4-oxadiazole
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | N'-[(3,4-dimethoxy-5-nitrobenzoyl)oxy]acetamidine | HCID 53789064 | — |
| 용매 | Acetic Acid | HCID 176 | — |
| 생성물 | 5-(3,4-Dimethoxy-5-nitrophenyl)-3-methyl-1,2,4-oxadiazole | HCID 21459080 | — |
반응 단계
2.0 g of N'-[(3,4-dimethoxy-5-nitrobenzoyl)oxy] acetamidine are held at reflux temperature for 1 hour in 20 ml of glacial acetic acid. After distillation of the acetic acid, the crystalline residue is recrystallized from ether/hexane. There is obtained 5-(3,4-dimethoxy-5-nitrophenyl)-3-methyl-1,2,4-oxadiazole in the form of colorless crystals of m.p. 111°.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05633371 |
| 출처 데이터셋 | uspto-grants-1997_05 |
| ORD ID | ord-f347339a177f4ab8a08748288e49560e |
| 출처 메모 | uspto-grants-1997_05 |