Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
3-Fluorobenzylic alcohol → (R)-1-[4-(3-fluoro-benzyloxy)-phenyl]-5-oxo-pyrrolidine-3-carboxylic acid methyl ester
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 3-Fluorobenzylic alcohol | HCID 68008 | — |
| 반응물 | (R)-1-(4-hydroxyphenyl)-5-oxo-pyrrolidine-3-carboxylic acid methyl ester | HCID 785702 | — |
| 생성물 | (R)-1-[4-(3-fluoro-benzyloxy)-phenyl]-5-oxo-pyrrolidine-3-carboxylic acid methyl ester | HCID 68615673 | — |
반응 단계
In an analogous manner to that described in Example 28b), the alkylation of the (R)-1-(4-hydroxy-phenyl)-5-oxo-pyrrolidine-3-carboxylic acid methyl ester [Example 28a)] with 3-fluorobenzylalcohol yields the (R)-1-[4-(3-fluoro-benzyloxy)-phenyl]-5-oxo-pyrrolidine-3-carboxylic acid methyl ester as a white solid. MS: m/e=344 (M+H)+.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07037935B2 |
| 출처 데이터셋 | uspto-grants-2006_05 |
| ORD ID | ord-99b316ff25974ffbb043ed300fcb5cf7 |
| 출처 메모 | uspto-grants-2006_05 |