Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Dicyclohexylcarbodiimide → 4-(5-Undecyl-pyrimidin-2-yl)phenyl 5-ethyl-furan-2-carboxylate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Dicyclohexylcarbodiimide | HCID 10868 | — |
| 반응물 | 5-Ethylfuran-2-carboxylic acid | HCID 247392 | — |
| 반응물 | 4-(5-Undecylpyrimidin-2-yl)phenol | HCID 135619682 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | 4-(5-Undecyl-pyrimidin-2-yl)phenyl 5-ethyl-furan-2-carboxylate | HCID 15514981 | — |
반응 단계
4.9 g of 4-(5-undecyl-pyrimidin-2-yl)phenol, 1.4 g of 5-ethyl-2-furancarboxylic acid (prepared as described by Perry et al., Appl. Organomet. Chem. 10, 389–392 (1996) from furan-2-carboxylic acid; m.p. 90° C.) and 2.1 g of dicyclohexylcarbodiimide are stirred for 24 h in 50 ml of dichloromethane at room temperature. Filtration, removal of the dichloromethane by distillation, purification by chromatography (silica gel; dichloromethane/heptane) and recrystallization from acetonitrile affords the target compound as colorless crystals having the phase sequence X 80 (N62) I.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07052742B1 |
| 출처 데이터셋 | uspto-grants-2006_05 |
| ORD ID | ord-f8cd3871948e49d4b8c8754327fecc45 |
| 출처 메모 | uspto-grants-2006_05 |