Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Ethanol → HCID 70618683, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Ethanol | HCID 702 | — |
| 반응물 | 1-(6-Methylpyridin-3-yl)butane-1,3-dione | HCID 20212814 | — |
| 반응물 | HCID 20352683 | HCID 20352683 | — |
| 용매 | Formic Acid | HCID 284 | — |
| 생성물 | HCID 70618683 | HCID 70618683 | 89% |
반응 단계
54.0 g of 1-(p-[4-methoxybutoxy]-phenoxy)-3-aminopropan-2-ol ##STR76## 37.3 g of 6-methylnicotinoyl-acetone ##STR77## 400 ml of ethanol and 0.1 ml of formic acid are heated to 50° for 1 hour and stirred at room temperature for a further 20 hours. Filtration gives 61.3 g of 1-(2-[6-methylnicotinoyl]-1-methylvinylamino)-3-(p-[4-methoxybutoxy]-phenoxy)-propan-2-ol ##STR78## Melting point: 143°-145°. A further 15.0 g of the same substance can be obtained from the filtrate. Yield: 89% of theory.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04066768 |
| 출처 데이터셋 | uspto-grants-1978_01 |
| ORD ID | ord-e803bd29ad03488d9c7084cea1930d69 |
| 출처 메모 | uspto-grants-1978_01 |