Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-Methoxybenzenesulfonyl chloride → 5-Bromo-1-(4-methoxybenzenesulfonyl)-7-nitroindoline
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-Methoxybenzenesulfonyl chloride | HCID 7401 | — |
| 반응물 | 5-Bromo-7-nitroindoline | HCID 3018911 | — |
| 용매 | Pyridine | HCID 1049 | — |
| 생성물 | 5-Bromo-1-(4-methoxybenzenesulfonyl)-7-nitroindoline | HCID 68612665 | — |
반응 단계
The preparation involved a straightforward reaction sequence with high yields (overall 48-56% in three or four steps). The commercially available 5-bromo-7-nitroindoline (16) was reacted with the 4-methoxybenzenesulfonyl chloride in pyridine to afford the 5-bromo-1-(4-methoxybenzenesulfonyl)-7-nitroindoline (17).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07741495B2 |
| 출처 데이터셋 | uspto-grants-2010_06 |
| ORD ID | ord-84ed2333241244709d8e914e59951045 |
| 출처 메모 | uspto-grants-2010_06 |