Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Bromine → 2-(6-amino-8-bromo-9H-purin-9-yl)ethanol
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Bromine | HCID 24408 | — |
| 반응물 | 2-(6-Aminopurin-9-yl)ethanol | HCID 242652 | — |
| 용매 | sodium;acetic acid;acetate | HCID 178476574 | — |
| 생성물 | 2-(6-amino-8-bromo-9H-purin-9-yl)ethanol | HCID 44572469 | 43% |
반응 단계
To a solution of 10 g 2-(6-amino-purin-9-yl)ethanol in 200 ml 0.5M AcONa/AcOH buffer pH 4 were added 4 ml of Br2. The resulting mixture was stirred at room temperature for 8 hours. The precipitated product was isolated, washed with water and crystallized from ethanol to give 6.13 g (43%) of the desired compound.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08173609B2 |
| 출처 데이터셋 | uspto-grants-2012_05 |
| ORD ID | ord-7c2c581a412e4451ae310470494ed016 |
| 출처 메모 | uspto-grants-2012_05 |