Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-Methyl-8-nitroquinoline → 2-Methyl-8-aminoquinoline
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-Methyl-8-nitroquinoline | HCID 13433 | — |
| 촉매 | Palladium | HCID 23938 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | 2-Methyl-8-aminoquinoline | HCID 140457 | 99.9% |
반응 단계
To a Pressure reaction bottle was added 5.0 g of 8-nitroquinaldine, 0.5 g 5% palladium on carbon, and 150 ml ethanol. The mixture was purged with hydrogen and then hydrogenated under 40 psi hydrogen for 16 hours. The catalyst was filtered off on a bed of celite. The solvent was removed, resulting in 4.2 g of a dark oil.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08182718B2 |
| 출처 데이터셋 | uspto-grants-2012_05 |
| ORD ID | ord-89f695c0d3fa4ffea39f48522a21f72b |
| 출처 메모 | uspto-grants-2012_05 |