Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-chloro-N-(2-methoxyethyl)acetamide → 6-{2-{Ethyl {4-[2-(2-methoxyethylamino)ethoxy]benzyl}amino}-4-methoxyphenyl}-5,6,7,8-tetrahydronaphthalen-2-ol
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-chloro-N-(2-methoxyethyl)acetamide | HCID 2386048 | — |
| 반응물 | HCID 57934562 | HCID 57934562 | — |
| 생성물 | 6-{2-{Ethyl {4-[2-(2-methoxyethylamino)ethoxy]benzyl}amino}-4-methoxyphenyl}-5,6,7,8-tetrahydronaphthalen-2-ol | HCID 58023083 | 13.9% |
반응 단계
Synthesized from pivalic acid 6-{2-[ethyl(4-hydroxybenzoyl)amino]-4-methoxyphenyl}-5,6,7,8-tetrahydronaphthalen-2-yl ester (25 mg) and 2-chloro-N-(2-methoxyethyl)acetamide (14 mg) according to an analogous synthetic method to Example 567 and purified by LC-MS, the title compound (3.5 mg) was obtained.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08399520B2 |
| 출처 데이터셋 | uspto-grants-2013_03 |
| ORD ID | ord-f8dd7c0536fa41d8b63252ef0bc2bf73 |
| 출처 메모 | uspto-grants-2013_03 |