참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Sodium Iodide | HCID 5238 | — |
| 반응물 | Potassium Carbonate | HCID 11430 | — |
| 반응물 | 2-Bromoethyl ethyl ether | HCID 61141 | — |
| 반응물 | 4-Bromo-2-ethoxyphenol | HCID 21877541 | — |
| 용매 | Dimethylformamide | HCID 6228 | — |
| 생성물 | 1-Bromo-3-ethoxy-4-(2-ethoxyethoxy)benzene | HCID 21995818 | — |
반응 단계
A suspension of 4-bromo-2-ethoxyphenol (8 g), bromoethylethyl ether (5 ml), sodium iodide (5.5 g) and potassium carbonate (10.2 g) in DMF (10 ml) was stirred under nitrogen atmosphere at 90° C. overnight. The solvent was evaporated, and to the residue was added water. The mixture was extracted with ethyl acetate. The organic layer was washed with water and saturated brine, and dried with anhydrous magnesium sulfate. The solvent was evaporated, and the residue was distilled under reduced pressure to give 1-bromo-3-ethoxy-4-(2-ethoxyethoxy)benzene (8.1 g) as yellow oil.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US06235771B1 |
|---|
| 출처 데이터셋 | uspto-grants-2001_05 |
|---|
| ORD ID | ord-634e959b69c5429c9d5a0e10160dfb97 |
|---|
| 출처 메모 | uspto-grants-2001_05 |
|---|
