Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Fludarabine Phosphate → Fludarabine phosphate magnesium salt
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Fludarabine Phosphate | HCID 30751 | — |
| 반응물 | Magnesium monoxide | HCID 6850729 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | Fludarabine phosphate magnesium salt | HCID 86755286 | 95% |
반응 단계
10.0 g of fludarabine phosphate at a purity of 97.5% is suspended in 100 ml of water within about 5 minutes, and magnesium oxide is added to this solution. The mixture is stirred for one more hour at room temperature and then filtered. The clear solution is poured into 200 ml of acetone, stirred for 1 more hour, and the crystallizate is separated by filtration. 10.0 g (95% of theory) of the fludarabine-phosphate magnesium salt is obtained.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07547776B1 |
| 출처 데이터셋 | uspto-grants-2009_06 |
| ORD ID | ord-d21ed0f6c92449e488827afdcd927451 |
| 출처 메모 | uspto-grants-2009_06 |