Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Methyl 3-(benzyloxy)-5-[4-(methanesulfonyl)phenoxy]benzoate → Methyl 3-hydroxy-5-(4-(methylsulfonyl)phenoxy)benzoate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Methyl 3-(benzyloxy)-5-[4-(methanesulfonyl)phenoxy]benzoate | HCID 53393370 | — |
| 촉매 | Palladium | HCID 23938 | — |
| 용매 | Tetrahydrofuran | HCID 8028 | — |
| 생성물 | Methyl 3-hydroxy-5-(4-(methylsulfonyl)phenoxy)benzoate | HCID 46941846 | 100.4% |
반응 단계
Methyl 3-(phenylmethyl)oxy-5-[4-(methylsulfonyl)phenoxy]benzoate (3.50 g, 8.50 mmol) was dissolved in THF (60 mL) followed by 10% palladium on carbon (500 mg). The reaction was then placed under a hydrogen atmosphere by an evacuation-backfill technique. The reaction was then stirred vigorously for 4 h followed by filtration and evaporation which afforded the title compound as an colourless oil (2.75 g, 100%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07745475B2 |
| 출처 데이터셋 | uspto-grants-2010_06 |
| ORD ID | ord-7bc23264b96942be9c3b1ccb95e8e4d8 |
| 출처 메모 | uspto-grants-2010_06 |