1-(4-ethoxyphenyl)-5-methoxy-2-methyl-1H-indole-3-carboxylic acid → HCID 57978137, 화합물

HRID 2055456

반응식

HRID 2055456 반응식
[NH:1]1[CH2:6][CH2:5][C:4]2([C:10]3[CH:11]=[CH:12][CH:13]=[CH:14][C:9]=3[C:8](=[O:15])[O:7]2)[CH2:3][CH2:2]1.[CH2:16]([O:18][C:19]1[CH:24]=[CH:23][C:22]([N:25]2[C:33]3[C:28](=[CH:29][C:30]([O:34][CH3:35])=[CH:31][CH:32]=3)[C:27]([C:36](O)=[O:37])=[C:26]2[CH3:39])=[CH:21][CH:20]=1)[CH3:17]>>[CH2:16]([O:18][C:19]1[CH:24]=[CH:23][C:22]([N:25]2[C:33]3[C:28](=[CH:29][C:30]([O:34][CH3:35])=[CH:31][CH:32]=3)[C:27]([C:36]([N:1]3[CH2:6][CH2:5][C:4]4([C:10]5[CH:11]=[CH:12][CH:13]=[CH:14][C:9]=5[C:8](=[O:15])[O:7]4)[CH2:3][CH2:2]3)=[O:37])=[C:26]2[CH3:39])=[CH:21][CH:20]=1)[CH3:17]

참가 물질

3

반응물 2

HCID 7421601-(4-ethoxyphenyl)-5-methoxy-2-methyl-1H-indole-3-carboxylic acidHCID 98342553H-spiro(isobenzofuran-1,4'-piperidin)-3-one

생성물 1

HCID 57978137HCID 57978137, 화합물

실험 절차

Following the general procedure I as described above, the acylation of 3H-spiro[2-benzofuran-1,4′-piperidin]-3-one prepared as described in example 16, with commercially available 1-(4-ethoxyphenyl)-5-methoxy-2-methyl-1H-indole-3-carboxylic acid, gave the title compound. ES-MS m/e (%): 511.5 (M+H+).

후처리

  1. customprepared

출처 및 근거

ORD 기록
ord-364e5adf91544d4aa855e8187513f9b9
출처 데이터셋
uspto-grants-2008_02
특허 번호
US07332501B2

연결된 노트

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