Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-Chloro-4-fluorocinnamic acid → (E)-3-(2-Chloro-4-fluoro-phenyl)-N-{1-[5-(1,1-difluoro-ethyl)-furan-2-ylmethyl]-1H-pyrazol-4-yl}-acrylamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-Chloro-4-fluorocinnamic acid | HCID 6257297 | — |
| 반응물 | HCID 66928549 | HCID 66928549 | — |
| 생성물 | (E)-3-(2-Chloro-4-fluoro-phenyl)-N-{1-[5-(1,1-difluoro-ethyl)-furan-2-ylmethyl]-1H-pyrazol-4-yl}-acrylamide | HCID 66929430 | — |
반응 단계
Following general procedure B, starting from 1-[5-(1,1-difluoro-ethyl)-furan-2-ylmethyl]-1H-pyrazol-4-ylamine and (E)-3-(2-chloro-4-fluoro-phenyl)-acrylic acid. LC-MS-conditions 05b: tR=1.12 min; [M+H]+=410.06.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08288419B2 |
| 출처 데이터셋 | uspto-grants-2012_10 |
| ORD ID | ord-9d49f6e8ad6c450390b95815d735ec78 |
| 출처 메모 | uspto-grants-2012_10 |