Alanine methyl ester hydrochloride → (S)-methyl 2-(6-(4-(3,5-dichloropyridin-4-ylamino)-7-methoxy-2-oxo-2H-chromen-8-yloxy)hexanamido)propanoate

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The title compound was prepared from Ala-OMe•HCl and 6-(4-(3,5-dichloropyridin-4-ylamino)-7-methoxy-2-oxo-2H-chromen-8-yloxy)hexanoic acid (Example 44) following the procedure outlined in Example 94. 1H NMR (400 MHz, DMSO-d6): δ 9.51 (s, 1H), 8.81 (s, 2H), 8.20 (d, 1H), 7.94 (d, 1H), 7.20 (d, 1H), 4.63 (s, 1H), 4.22 (m, 1H), 3.96 (t, 2H), 3.92 (s, 3H), 3.58 (s, 3H), 2.11 (t, 2H), 1.68 (m, 2H), 1.54 (m, 2H), 1.43 (m, 2H), 1.23 (d, 3H); MS (ESI): 552.0.

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