Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Acetic Acid → 4-Cyclohexylcyclohexylidenephosphorohydrazidic Acid, Diethyl Ester
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Acetic Acid | HCID 176 | — |
| 반응물 | (1,1'-Bicyclohexyl)-4-one | HCID 41690 | — |
| 반응물 | Phosphorohydrazidic acid, diethyl ester | HCID 143340 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | 4-Cyclohexylcyclohexylidenephosphorohydrazidic Acid, Diethyl Ester | HCID 85540745 | — |
반응 단계
To a solution of 4-cyclohexylcyclohexanone (27.04 g) and acetic acid (3 ml) in CH2Cl2 (400 ml) was added a solution of diethyl phosphorohydrazidate (28.91 g) in CH2Cl2 (100 ml). The reaction was stirred at room temperature for 27 hours and then was concentrated under reduced pressure. Toluene was added (2×) and removed under reduced pressure in order to aid in the removal of acetic acid by co-distillation. The residual yellow liquid was the product and was used without further purification. TLC Rf=0.52 (20% acetone in CH2Cl2, silica gel).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05187299 |
| 출처 데이터셋 | uspto-grants-1993_02 |
| ORD ID | ord-19c281feeef0428394f5cc47cba1bd4a |
| 출처 메모 | uspto-grants-1993_02 |