Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-(methylsulfonyl)-Biphenyl-2-carboxylic acid → (4-Methanesulfonyl-biphenyl-2-yl)-(2-trifluoromethyl-7,8-dihydro-5H-[1,6]naphthyridin-6-yl)-methanone
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-(methylsulfonyl)-Biphenyl-2-carboxylic acid | HCID 57445254 | — |
| 반응물 | 2-(Trifluoromethyl)-5,6,7,8-tetrahydro-1,6-naphthyridine hydrochloride | HCID 57445256 | — |
| 생성물 | (4-Methanesulfonyl-biphenyl-2-yl)-(2-trifluoromethyl-7,8-dihydro-5H-[1,6]naphthyridin-6-yl)-methanone | HCID 11576214 | — |
반응 단계
Prepared in analogy to example 1.1 from 2-trifluoromethyl-5,6,7,8-tetrahydro-[1,6]naphthyridine hydrochloride (CA [741736-98-1]; WO2004069162) and 4-methanesulfonyl-biphenyl-2-carboxylic acid (example 2.5). MS (m/e): 461.3 (M+H+).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07442710B2 |
| 출처 데이터셋 | uspto-grants-2008_10 |
| ORD ID | ord-16dc8279527f4417ac1db322bf3f285d |
| 출처 메모 | uspto-grants-2008_10 |