Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hydrochloric Acid → N-(3-tert-butylphenyl)-4-methylpiperidine-4-carboxamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hydrochloric Acid | HCID 313 | — |
| 반응물 | HCID 86635224 | HCID 86635224 | — |
| 용매 | Methanol | HCID 887 | — |
| 생성물 | N-(3-tert-butylphenyl)-4-methylpiperidine-4-carboxamide | HCID 67036907 | — |
반응 단계
tert-Butyl 4-(3-tert-butylphenylcarbamoyl)-4-methylpiperidine-1-carboxylate from step A (0.4 g, 1.07 mmol) was treated with HCl (4.0 N in dioxane, 1.3 mL, 5.34 mmol) in methanol (5.0 mL) at 50° C. for 30 minutes. The mixture was concentrated to give the title compound as the hydrochloride salt in quantitative yield. MS (ES+) [M+H]+=275.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08193202B2 |
| 출처 데이터셋 | uspto-grants-2012_06 |
| ORD ID | ord-361d2af2da5940e2b12b405634062e3a |
| 출처 메모 | uspto-grants-2012_06 |