참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Sodium Hydroxide | HCID 14798 | — |
| 반응물 | 2-Bromobenzoyl chloride | HCID 23542 | — |
| 반응물 | N'-t-butyl-N-(2-pyridinecarbonyl)hydrazine | HCID 15767542 | — |
| 용매 | Toluene | HCID 1140 | — |
| 생성물 | N'-t-butyl-N-(2-pyridinecarbonyl)-N'-(2-bromobenzoyl)hydrazine | HCID 15767545 | 49.3% |
반응 단계
An aqueous solution of sodium hydroxide (1.24 g of 50% NaOH diluted with 5 ml of water) was added to a solution of N'-t-butyl-N-(2-pyridinecarbonyl)hydrazine (1.0 g, 0.00518 mol) in 20 ml of toluene at 23° C. The mixture was cooled and treated with 2-bromobenzoyl chloride (1.137 g, 0.00518 mol). The mixture was then stirred at 23° C. overnight. The solids were removed by filtration, washed with water and dried to afford 0.96 g of N'-t-butyl-N-(2-pyridinecarbonyl)-N'-(2-bromobenzoyl)hydrazine as a white solid: m.p. 179°-180° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US05424333 |
|---|
| 출처 데이터셋 | uspto-grants-1995_06 |
|---|
| ORD ID | ord-0f307f2f5ef948bcadb70ac44f63307b |
|---|
| 출처 메모 | uspto-grants-1995_06 |
|---|
