Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Aluminium lithium hydride → 3-Methyl-5-(1-methyl-2(S)-pyrrolidinyl)isoxazole
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Aluminium lithium hydride | HCID 21226445 | — |
| 반응물 | 1-(1-CBZ-2(S)-pyrrolidinyl)-1-buten-3-one oxime | HCID 86748737 | — |
| 용매 | Tetrahydrofuran | HCID 8028 | — |
| 생성물 | 3-Methyl-5-(1-methyl-2(S)-pyrrolidinyl)isoxazole | HCID 119380 | — |
반응 단계
The Cbz-protected compound of step 23d is reacted with LAH in THF at 0° C. as described in Example 24 below, and the title compound is isolated in pure form by extraction with ethyl acetate and distillation under high vacuum.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05424444 |
| 출처 데이터셋 | uspto-grants-1995_06 |
| ORD ID | ord-daec843a89594a82897f91c6ed9e178d |
| 출처 메모 | uspto-grants-1995_06 |