Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1,2,3,4-Tetrahydro-1-naphthoic acid → N-(6-isopropylpyridin-3-yl)-1,2,3,4-tetrahydronaphthalene-1-carboxamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1,2,3,4-Tetrahydro-1-naphthoic acid | HCID 12598146 | — |
| 반응물 | 6-(Propan-2-yl)pyridin-3-amine | HCID 17854288 | — |
| 생성물 | N-(6-isopropylpyridin-3-yl)-1,2,3,4-tetrahydronaphthalene-1-carboxamide | HCID 17854426 | 86.4% |
반응 단계
By the reaction and treatment in the same manner as in Preparation Example 11 using 1,2,3,4-tetrahydronaphthalene-1-carboxylic acid (1.51 g) and 5-amino-2-isopropylpyridine (1.17 g) as starting materials, N-(6-isopropylpyridin-3-yl)-1,2,3,4-tetrahydronaphthalene-1-carboxamide (2.18 g) was obtained. melting point: 155.7° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08198454B2 |
| 출처 데이터셋 | uspto-grants-2012_06 |
| ORD ID | ord-059f4241356a4b3eacb0ba0fe5a8db36 |
| 출처 메모 | uspto-grants-2012_06 |