Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
5-Methyl-1,2-oxazole-4-sulfonyl chloride → 8-(5-Methyl-isoxazole-4-sulfonyl)-2-(4-trifluoromethoxy-phenyl)-2,8-diaza-spiro[4.5]decan-1-one
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 5-Methyl-1,2-oxazole-4-sulfonyl chloride | HCID 2776141 | — |
| 반응물 | 2-(4-Trifluoromethoxy-phenyl)-2,8-diaza-spiro[4.5]decan-1-one acetic acid salt | HCID 66787333 | — |
| 생성물 | 8-(5-Methyl-isoxazole-4-sulfonyl)-2-(4-trifluoromethoxy-phenyl)-2,8-diaza-spiro[4.5]decan-1-one | HCID 59577999 | — |
반응 단계
The title compound was prepared in analogy to example 180 step D from 2-(4-trifluoromethoxy-phenyl)-2,8-diaza-spiro[4.5]decan-1-one acetic acid salt (described in example 180 step C) and 5-methyl-isoxazole-4-sulfonyl chloride. White solid. MS (ESI): 460.3 (MH+).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08329904B2 |
| 출처 데이터셋 | uspto-grants-2012_12 |
| ORD ID | ord-21f3c9c489fa44ccbe734e4bf4ca2459 |
| 출처 메모 | uspto-grants-2012_12 |