Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Thionyl Chloride → 5-(Chloromethyl)-2-methylpyrimidine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Thionyl Chloride | HCID 24386 | — |
| 반응물 | (2-Methylpyrimidin-5-yl)methanol | HCID 14686706 | — |
| 생성물 | 5-(Chloromethyl)-2-methylpyrimidine | HCID 14686699 | — |
반응 단계
A solution of (2-methylpyrimidin-5-yl)methanol (95 mg, 0.77 mmol) in thionyl chloride (1 mL) was stirred at room temperature for 1 h. The mixture was concentrated to dryness and used without purification. LCMS MH+ 143.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US09359359B2 |
| 출처 데이터셋 | uspto-grants-2016_06 |
| ORD ID | ord-2a2b5487c26648388f8b0c144ea6dbcf |
| 출처 메모 | uspto-grants-2016_06 |