Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Tributylstannane → 2-Ethoxycarbonylimino-3-(3-trifluoromethylphenyl)thiazoline
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Tributylstannane | HCID 5948 | — |
| 반응물 | Benzoyl Peroxide | HCID 7187 | — |
| 반응물 | 2-Ethoxycarbonylimino-3-(3-trifluoromethylpheny)-5-bromothiazoline | HCID 54096993 | — |
| 용매 | Tetrahydrofuran | HCID 8028 | — |
| 생성물 | 2-Ethoxycarbonylimino-3-(3-trifluoromethylphenyl)thiazoline | HCID 54352089 | 75.8% |
반응 단계
A solution of 2-ethoxycarbonylimino-3-(3-trifluoromethylphenyl)-5-bromothiazoline (4.7 g), tributyltin hydride (6.9 g) and a catalytic amount of benzoyl peroxide in tetrahydrofuran (100 ml) was refluxed for 10 hours. The solvent was removed by distillation, and the residue was washed with hexane. Recrystallization from a mixture of hexane and ethanol gave 2.85 g of 2-ethoxycarbonylimino-3-(3-trifluoromethylphenyl) thiazoline (Compound (xii)).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05426188 |
| 출처 데이터셋 | uspto-grants-1995_06 |
| ORD ID | ord-c6888d67ee3542789f12cd043e1c654d |
| 출처 메모 | uspto-grants-1995_06 |