Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
(4-Chloro-3-methoxyphenyl)boronic acid → HCID 68938275, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | (4-Chloro-3-methoxyphenyl)boronic acid | HCID 23005377 | — |
| 반응물 | 5-bromomethylene-1-chloro-10,11dihydro-5H-dibenzo[a,d]cycloheptene | HCID 68891389 | — |
| 생성물 | HCID 68938275 | HCID 68938275 | 71% |
반응 단계
Following procedures essentially as described in Example 219, below, and using 4-chloro-3-methoxyphenylboronic acid (160 mg,0.85 mmol) with 5-bromomethylene-1-chloro-10,11-dihydro-5H-dibenzo[a,d]cycloheptene (249 mg, 0.78 mmol) to give 440 mg crude product. Purify by chromatography to give 210 mg (71%) colorless oil. HPLC (ISO90-10M) shows 51% at t=7.62 min and 45% at t=9.86 min.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07411072B2 |
| 출처 데이터셋 | uspto-grants-2008_08 |
| ORD ID | ord-0ebd9318c8864a898f543e938ac47807 |
| 출처 메모 | uspto-grants-2008_08 |