참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Ammonia | HCID 222 | — |
| 반응물 | Benzoic acid, 3-methyl-2-nitro-, methyl ester | HCID 79621 | — |
| 용매 | Methanol | HCID 887 | — |
| 생성물 | 3-Methyl-2-nitrobenzamide | HCID 3271371 | — |
반응 단계
Methyl 3-methyl-2-nitrobenzoate (10.02 g, 51.3 mmol) was added to a 7N solution of ammonia in methanol (50 mL) and the mixture was heated at 100° C. in a Fisher-Porter tube for 3 hours. The solution was then cooled, concentrated and triturated with dichloromethane to give the title compound of Step A as a white solid (14 g).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US07375232B2 |
|---|
| 출처 데이터셋 | uspto-grants-2008_05 |
|---|
| ORD ID | ord-056bd7b515214900876475b49e95e6cf |
|---|
| 출처 메모 | uspto-grants-2008_05 |
|---|
