Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Sodium Hydroxide → 4'-Methyl-biphenyl-3-carboxylic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Sodium Hydroxide | HCID 14798 | — |
| 반응물 | 4'-Methyl-biphenyl-3-carboxylic acid ethyl ester | HCID 10728754 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | 4'-Methyl-biphenyl-3-carboxylic acid | HCID 2773978 | 67.9% |
반응 단계
To a solution of ethyl 4'-methylbiphenyl-3-carboxylate (4.0 g) in ethanol (50 ml) was added a solution of 10 ml of 10% aqueous sodium hydroxide, and the mixture refluxed for 2 hours. Solvent was removed under reduced pressure, water added to the residue, and the solution filtered. The filtrate was acidified with dilute hydrochloric acid, and the white solid filtered off and dried under vacuum, yielding 2.4 g of 4'-methylbiphenyl-3-carboxylic acid m.p. 192° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05428037 |
| 출처 데이터셋 | uspto-grants-1995_06 |
| ORD ID | ord-db788f0e684c4545913753d0f555e1f7 |
| 출처 메모 | uspto-grants-1995_06 |