참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Water | HCID 962 | — |
| 반응물 | Ammonium Acetate | HCID 517165 | — |
| 반응물 | 4-Hydroxycoumarin | HCID 54682930 | — |
| 용매 | Ethylene Glycol | HCID 174 | — |
| 생성물 | 4-Aminocoumarin | HCID 820807 | 99.4% |
반응 단계
97.2 g of 4-hydroxycoumarin and 69.3 g of ammonium acetate in 300 ml of ethylene glycol are heated to 70° C. for 3 hours, whilst stirring, and to 160° C. for 6 hours, the mixture is cooled to 60° C., 1 liter of water is added, whilst stirring, and the mixture is cooled to room temperature. The colourless crystalline precipitate is filtered off, washed with water and dried in vacuo at 60° C. 96 g of 4-aminocoumarin in an almost pure form are obtained.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US04234488 |
|---|
| 출처 데이터셋 | uspto-grants-1980_11 |
|---|
| ORD ID | ord-a991ef93bd7c452db36474033f77f721 |
|---|
| 출처 메모 | uspto-grants-1980_11 |
|---|
