Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Acetic Acid → Indole, 5-bromo-3-(dimethylamino)methyl-
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Acetic Acid | HCID 176 | — |
| 반응물 | Dimethylamine | HCID 674 | — |
| 반응물 | Formaldehyde | HCID 712 | — |
| 반응물 | 5-Bromoindole | HCID 24905 | — |
| 용매 | 1,4-Dioxane | HCID 31275 | — |
| 생성물 | Indole, 5-bromo-3-(dimethylamino)methyl- | HCID 13249 | — |
반응 단계
This material was prepared by the method of Procedure 67B from 49.5 g. of 5-bromoindole, 20 ml. of 37% aqueous formaldehyde, 55 ml. of 25% aqueous dimethylamine, 250 ml. of acetic acid and 250 ml. of dioxane; yield 60.6 g., m.p. 154°-156° C. The structure was confirmed by examination of the NMR spectrum.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04234595 |
| 출처 데이터셋 | uspto-grants-1980_11 |
| ORD ID | ord-b8d02287528a42eeb37d82ed1423ce24 |
| 출처 메모 | uspto-grants-1980_11 |