Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Acetic Anhydride → 3-Hydroxy-3'-(trifluoromethyl)acrylophenone acetate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Acetic Anhydride | HCID 7918 | — |
| 반응물 | 1,4-Dioxane | HCID 31275 | — |
| 반응물 | 3-Hydroxy-3'-(trifluoromethyl)acrylophenone sodium salt | HCID 70590370 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | 3-Hydroxy-3'-(trifluoromethyl)acrylophenone acetate | HCID 70477828 | — |
반응 단계
A suspension of 12.0 g. of 3-hydroxy-3'-(trifluoromethyl)acrylophenone sodium salt in 75 ml. of dioxane and 10 ml. of acetic anhydride is stirred at room temperature for 2 hours and then poured into water. The precipitate is collected by filtration, dissolved in methylene chloride and then passed through a hydrous magnesium silicate column as described in Example 1, giving the desired product, m.p. 55°-5° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04236005 |
| 출처 데이터셋 | uspto-grants-1980_11 |
| ORD ID | ord-ce7f085a7a9b4a418043979685cee370 |
| 출처 메모 | uspto-grants-1980_11 |