Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Methyl iodide → 2-Methoxy-1,3-dimethyl-5-nitrobenzene
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Methyl iodide | HCID 6328 | — |
| 반응물 | Potassium Carbonate | HCID 11430 | — |
| 반응물 | 2,6-Xylenol, 4-nitro- | HCID 17030 | — |
| 반응물 | N2,N4-bis(3-methoxy-4-methoxycarbonylphenyl)-5-fluoro-2,4-pyrimidinediamine | HCID 22060643 | — |
| 생성물 | 2-Methoxy-1,3-dimethyl-5-nitrobenzene | HCID 139835 | — |
반응 단계
In a manner analogous to the preparation of N2,N4-bis[3-methoxy-4-(methoxycarbonyl)phenyl]-5-fluoro-2,4-pyrimidinediamine, the reaction of 2,6-dimethyl-4-nitrophenol (1.67 g, 10 mmol), potassium carbonate (13 g, 0.1 mol) and iodomethane (2.5 mL, 50 mmol) gave 2,6-dimethyl-1-methoxy-4-nitrobenzene. Hydrogenation of 2,6-dimethyl-1-methoxy-4-nitrobenzene gave 3,5-dimethyl-4-methoxyaniline.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07557210B2 |
| 출처 데이터셋 | uspto-grants-2009_07 |
| ORD ID | ord-319e4184c89c4f46801d35ef7e7360e2 |
| 출처 메모 | uspto-grants-2009_07 |