Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-Aminothiazole → N-[2-(2,3-Dimethoxyphenoxy)phenyl]-N'-(thiazol-2-yl)urea
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-Aminothiazole | HCID 2155 | — |
| 반응물 | 1-Fluoro-2-nitrobenzene | HCID 73895 | — |
| 반응물 | 2,3-Dimethoxyphenol | HCID 78828 | — |
| 반응물 | 2-(2,3-Dimethoxyphenoxy)aniline | HCID 66998935 | — |
| 생성물 | N-[2-(2,3-Dimethoxyphenoxy)phenyl]-N'-(thiazol-2-yl)urea | HCID 59732909 | 71% |
| 생성물 | 2-(2,3-Dimethoxyphenoxy)-1-nitrobenzene | HCID 66999086 | 64% |
반응 단계
2-(2,3-Dimethoxyphenoxy)-1-nitrobenzene (0.88 g, 64%) was prepared from 2,3-dimethoxyphenol (0.85 g, 5.5 mmol) and 1-fluoro-2-nitrobenzene (0.71 g, 5.0 mmol) following the general procedure A. This was reduced to 2-(2,3-dimethoxyphenoxy)aniline (0.57 g, 73%) following general procedure B. N-[2-(2,3-Dimethoxyphenoxy)phenyl]-N′-(thiazol-2-yl)urea (131 g, 71%) was prepared from 2-(2,3-dimethoxyphenoxy)aniline (123 mg, 0.5 mmol) and 2-aminothiazole (60 mg, 0.6 mmol) following the general procedure D.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | USRE045670E1 |
| 출처 데이터셋 | uspto-grants-2015_09 |
| ORD ID | ord-c886655731924bc080dcfd04835998c1 |
| 출처 메모 | uspto-grants-2015_09 |