Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-Aminothiazole → 1-(1-Methylethoxy)-2-nitrobenzene
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-Aminothiazole | HCID 2155 | — |
| 반응물 | Isopropanol | HCID 3776 | — |
| 반응물 | 2-(1-Methylethoxy)benzenamine | HCID 34436 | — |
| 반응물 | 1-Fluoro-2-nitrobenzene | HCID 73895 | — |
| 생성물 | 1-(1-Methylethoxy)-2-nitrobenzene | HCID 197180 | 70% |
| 생성물 | N-(2-Isopropoxyphenyl)-N'-thiazolylurea | HCID 47363733 | 60% |
반응 단계
2-(Isopropoxy)-1-nitrobenzene (317 mg, 70%) was prepared from isopropyl alcohol (0.24 ml, 3.0 mmol) and 1-fluoro-2-nitrobenzene (0.36 g, 2.5 mmol) following the general procedure G. This was reduced to 2-(isopropoxy)aniline (198 mg, 75%) following general procedure B. N-(2-Isopropoxyphenyl)-N′-thiazolylurea (218 mg, 60%) was prepared from 2-(isopropoxy)aniline (198 mg, 01.3 mmol) and 2-aminothiazole (150 mg, 1.5 mmol) following the general procedure D.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | USRE045670E1 |
| 출처 데이터셋 | uspto-grants-2015_09 |
| ORD ID | ord-69d2c83747284e9093266df914744f44 |
| 출처 메모 | uspto-grants-2015_09 |