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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 228599생성일: 2026년 10월 24일

3-Hydroxybenzophenone → {3-[(6,7-Dimethoxy-4-quinolyl)oxy]phenyl}phenylmethanone

https://huagongshe.com/ko/reaction/228599

반응식

참여 물질

역할이름HCID투입량
반응물3-HydroxybenzophenoneHCID 83050—
반응물4-Chloro-6,7-dimethoxyquinolineHCID 459610—
반응물Sodium BicarbonateHCID 516892—
생성물{3-[(6,7-Dimethoxy-4-quinolyl)oxy]phenyl}phenylmethanoneHCID 5390720565.3%

반응 조건

온도170 °C

반응 단계

4-Chloro-6,7-dimethoxyquinoline (112 mg) and 3-hydroxybenzophenone (297 mg) were mixed together, and the mixture was heated at 170° C. for 10 min. A saturated aqueous sodium hydrogencarbonate solution was added thereto, and the mixture was extracted with ethyl acetate. The organic layer was washed with saturated brine, was dried over sodium sulfate, and was then concentrated. The residue was subjected to separation and purification by column chromatography on silica gel using hexane-acetone as a solvent to give the title compound (126 mg, yield 65%).

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US07560558B2
출처 데이터셋uspto-grants-2009_07
ORD IDord-7f9cab0a07a442abbf9e7ddac8cc2348
출처 메모uspto-grants-2009_07