Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Epibromohydrin → 8-Phenyloctyloxymethyloxirane
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Epibromohydrin | HCID 18430 | — |
| 반응물 | Sodium hydride | HCID 24758 | — |
| 반응물 | 8-Phenyloctan-1-ol | HCID 517850 | — |
| 용매 | Dimethylformamide | HCID 6228 | — |
| 생성물 | 8-Phenyloctyloxymethyloxirane | HCID 21474710 | — |
반응 단계
A procedure similar to that described in Preparation 46 was repeated, except that 4 g of 8-phenyloctyl alcohol, 3.18 ml of epibromohydrin, 0.85 g of sodium hydride (as a 55% by weight dispersion in mineral oil) and 80 ml of anhydrous dimethylformamide were used, to give 2.42 g of the title compound having an Rf value of 0.51 (on silica gel thin layer chromatography, using a 1:6 by volume mixture of ethyl acetate and hexane as the developing solvent).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05688823 |
| 출처 데이터셋 | uspto-grants-1997_11 |
| ORD ID | ord-10af86dee11b4b3ea5b745844875f7d8 |
| 출처 메모 | uspto-grants-1997_11 |