Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2,5-Dimethoxybenzenesulfonyl chloride → 2,5-Dimethoxy-N-[2-[(phenylsulfonyl)amino]4-(1-piperazinyl)phenyl]benzenesulfonamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2,5-Dimethoxybenzenesulfonyl chloride | HCID 137025 | — |
| 반응물 | N-(2-amino-5-(4-boc-1-piperazinyl)-phenyl)-benzenesulfonamide | HCID 22272479 | — |
| 생성물 | 2,5-Dimethoxy-N-[2-[(phenylsulfonyl)amino]4-(1-piperazinyl)phenyl]benzenesulfonamide | HCID 10302090 | — |
반응 단계
2,5-Dimethoxy-N-[2-[(phenylsulfonyl)amino]-4-(1-piperazinyl)phenyl]benzenesulfonamide was synthesized from of N-{2-amino-5-(4-t-butyloxycarbonyl-piperazinyl)-phenyl}benzenesulfonamide and 2,5-dimethoxybenzenesulfonylchloride (57 mg, 0.239 mmol) according to general method 3 to give 60 mg of a purple solid. MS (posES-FIA) m/z=Found: 533.1; Calcd: 533.14; 1H-NMR δ 7.68-7.48 (m, 5H), 7.16-7.05 (m, 4H), 6.69 (dd, 1H), 6.42 (d, 1H), 4.03 (s, 3H), 3.69 (s, 3H), 3.26-3.10 (m, 8H).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07566715B2 |
| 출처 데이터셋 | uspto-grants-2009_07 |
| ORD ID | ord-c7e1de708b734e6b98662cffa745cfb1 |
| 출처 메모 | uspto-grants-2009_07 |