Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Diethyl Ether → 2-Methylbutyl 4-(4'-carbobenzoxyoxybenzoyloxy)benzoate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Diethyl Ether | HCID 3283 | — |
| 반응물 | Benzoic acid, 4-hydroxy-, 2-methylbutyl ester | HCID 13530949 | — |
| 반응물 | 4-Carbobenzoxyoxybenzoyl chloride | HCID 19734054 | — |
| 용매 | Pyridine | HCID 1049 | — |
| 용매 | Tetrahydrofuran | HCID 8028 | — |
| 생성물 | 2-Methylbutyl 4-(4'-carbobenzoxyoxybenzoyloxy)benzoate | HCID 19734060 | 63% |
반응 단계
A solution of 16 m moles(3.3 g) of the above 4-hydroxybenzoic acid 2-methylbutyl ester in 20 ml of THF and 40 ml of pyridine was cooled, and a THF solution of 10 m moles(2.9 g) of the above 4-carbobenzoxyoxybenzoyl chloride was added dropwise. The mixture was returned slowly to room temperature, then stirred for 8 hours. After the reaction, the reaction mixture was ether extracted and concentrated, and then purified by column chromatography to obtain 2.9 g of 4-(4'-carbobenzoxyoxybenzoyloxy)benzoic acid 2-methylbutyl ester [m.p. 64.4°-65.4° C⟧ (yield: 63%)
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04844835 |
| 출처 데이터셋 | uspto-grants-1989_07 |
| ORD ID | ord-9ae0164c134f4c678979543892b72d2a |
| 출처 메모 | uspto-grants-1989_07 |